Dihexa 10mg | 20-Vial Kit | HGF/MET Nootropic Peptide | High-Dose Cognitive Research
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Dihexa 10mg | 20-Vial Kit — HGF/MET agonist heptapeptide (PNB-0408) — activates hepatocyte growth factor receptor to drive hippocampal synaptogenesis and dendritic spine density; studied for cognitive enhancement and memory improvement. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
$510.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
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What is Dihexa (High-Dose)??
Dihexa (PNB-0408, CAS 1239264-98-2) is a highly CNS-penetrant HGF/MET-potentiating peptidomimetic that drives de novo synaptogenesis — estimated at 10⁷-fold greater potency than BDNF for new dendritic spine formation. This 10mg/vial high-dose format supports dose-escalation protocols, multi-cohort neurodegeneration studies, transdermal delivery experiments, and long-duration cognitive paradigms where larger quantities per session are required. Molecular formula C₂₄H₃₉N₃O₄, MW 437.58 g/mol.
Research Applications
High-Dose Synaptogenesis
Dose-escalation dendritic spine density, concentration-response at HGF/MET receptor
Extended Cognitive Studies
Multi-week spatial learning, fear conditioning, and NOR paradigms requiring higher peptide reserves
Transdermal Delivery Research
Lipophilicity-driven skin penetration studies, bioavailability comparison vs. sc/ip routes
Neurodegeneration Reversal
High-dose Alzheimer’s-model synapse recovery, AChE-lesion and Aβ model synaptogenesis restoration
Neuroplasticity Mechanisms
LTP, AMPA/NMDA receptor trafficking, PSD-95 clustering under sustained HGF/MET activation
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 1239264-98-2 |
| Also Known As | PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide |
| Molecular Formula | C₂₄H₃₉N₃O₄ |
| Molecular Weight | 437.58 g/mol |
| Mechanism | HGF/MET receptor complex potentiation → synaptogenesis — 10mg/vial high-dose |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
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Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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