Follistatin-344 1mg | 20-Vial Kit | FST-344 | Myostatin & Activin Inhibitor Research

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Follistatin 1mg | 20-Vial Kit — Activin and myostatin binding glycoprotein (FST-344) — sequesters TGF-β superfamily ligands including myostatin (GDF-8) and activins to suppress receptor signalling, studied for muscle hypertrophy models. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

🌏 International shipping: 7–14 days

$1,150.00

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

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What is Follistatin??

Follistatin (FST-344, CAS 122956-17-2) is a single-chain glycoprotein (MW ~35 kDa for FST-344 isoform) belonging to the TGF-β superfamily binding protein class. It acts as a potent endogenous inhibitor of activins, myostatin (GDF-8), GDF-11, GDF-9, and BMPs by binding these ligands with high affinity and sequestering them from their receptors. FST-344 is the circulating, proteoglycan-binding–deficient isoform with broader systemic distribution than FST-288. It is a key research tool for studying muscle hypertrophy, fertility (FSH/activin axis), bone formation, and TGF-β pathway biology.

Research Applications

Myostatin Inhibition

GDF-8 sequestration, muscle fibre hypertrophy, atrophy model reversal — compared to ACE-031 and MSTN antibodies

Activin/FSH Axis

Activin A/B neutralisation, FSH suppression in pituitary research, ovarian folliculogenesis

Bone Formation

BMP-2/4/7 modulation, osteoblast differentiation, bone mineral density studies

Reproductive Biology

Gonadal steroidogenesis, spermatogenesis, granulosa cell function, follicle dynamics

TGF-β Superfamily Profiling

Broad ligand-trap characterisation across activin, GDF, and BMP family members

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 122956-17-2
Isoform FST-344 (systemic, heparin-low-affinity isoform)
Molecular Weight ~35 kDa (glycosylated)
Peptide Type Recombinant glycoprotein / TGF-β superfamily ligand trap
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 International shipping: 7–14 days

Frequently asked questions

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