FOXO4-DRI 5mg | 20-Vial Kit | Anti-Aging
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QSC FOXO4-DRI (FOXO4-p53 interaction inhibitor) — ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
$650.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
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What is FOXO4-DRI?
FOXO4-DRI (FOXO4-p53 interaction inhibitor — senolytic D-peptide) is a 18-amino acid retro-inverso D-amino acid peptide. Retro-inverso D-peptide disrupting the FOXO4-p53 protein-protein interaction in senescent cells, enabling p53 nuclear export and intrinsic apoptosis specifically in p21-high senescent cells. Spares normal proliferating and quiescent cells — selective senolytic without systemic toxicity in mouse models.
Research Applications
Senolytic Research
Selective senescent cell clearance — p21-high cell apoptosis
FOXO4-p53 Biology
Protein-protein interaction disruption, p53 nuclear localisation
Cellular Senescence
p21/p16 pathway, SA-β-gal markers, SASP reduction models
Healthspan Extension
Aged and fast-ageing mouse model healthspan and tissue function
vs Other Senolytics
Comparison with navitoclax, dasatinib+quercetin mechanism
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | Not publicly standardized |
| Molecular Formula | Sequence-specific peptide (FOXO4-derived D-retro-inverso analog) |
| Peptide Type | Senolytic Peptide / FOXO4-p53 Interaction Inhibitor |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
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A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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