Gonadorelin 5mg | 10-Vial Kit | GnRH Decapeptide | HPG Axis & Gonadotropin Research
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Gonadorelin 5mg | 10-Vial Kit — Native GnRH decapeptide — binds pituitary GnRH receptors to stimulate pulsatile LH and FSH secretion for HPG axis research, fertility models, and testosterone restoration protocols. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
$240.00
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
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What is Gonadorelin??
Gonadorelin (CAS 33515-09-2) is the synthetic form of endogenous gonadotropin-releasing hormone (GnRH / LHRH) — a 10-amino acid hypothalamic decapeptide (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂). Molecular formula C₅₅H₇₅N₁₇O₁₃, MW 1182.31 g/mol. Released in pulses from hypothalamic GnRH neurons, it binds the GnRHR (Gq/PLC/IP₃) on anterior pituitary gonadotrophs — stimulating LH and FSH synthesis and secretion. Pulsatile gonadorelin activates the HPG axis; continuous administration causes receptor downregulation and gonadotropin suppression — making it the definitive tool for studying pulse-dependent HPG axis regulation.
Research Applications
HPG Axis Pulsatility
Pulsatile vs. continuous GnRHR stimulation, LH/FSH pulse amplitude and frequency regulation
GnRH Receptor Pharmacology
GnRHR binding kinetics, Gq/PLC/IP₃ signalling, receptor internalisation, desensitisation
Gonadotropin Secretion
LH and FSH release from anterior pituitary gonadotrophs, surge vs. tonic secretion modelling
Male Reproductive Research
Testosterone axis (GnRH→LH→Leydig→T), spermatogenesis, hypogonadotropic hypogonadism models
Female Reproductive Biology
Folliculogenesis, ovulation induction, estradiol/progesterone cycling, PCOS models
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 33515-09-2 |
| Also Known As | GnRH, LHRH, Luteinising Hormone-Releasing Hormone |
| Sequence | pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH₂ |
| Molecular Formula | C₅₅H₇₅N₁₇O₁₃ |
| Molecular Weight | 1182.31 g/mol |
| Peptide Type | Endogenous hypothalamic decapeptide / GnRHR agonist |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
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Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
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