HGH Fragment 176-191 10mg | 20-Vial Kit | Lipolytic Peptide
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HGH Fragment 176-191 10mg | 20-Vial Kit — GH C-terminal fragment (residues 176-191) — activates β3-adrenergic receptors to drive fat oxidation without activating growth hormone receptor (GHR) or stimulating IGF-1. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
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What is HGH Fragment 176-191?
HGH Fragment 176-191 (Native GH C-terminal fragment — lipolytic peptide) is a 16-amino acid native GH C-terminal fragment. Native C-terminal fragment of human growth hormone (residues 176-191) activating lipolysis via beta-3 adrenergic receptor without GH receptor binding. Adipose-selective lipolytic activity identical mechanistic pathway to AOD-9604 but using the native (non-Tyr modified) sequence.
Research Applications
Native GH Fragment Research
Structure-activity comparison using native vs modified (AOD-9604) sequence
Beta-3 AR Lipolysis
Adipocyte HSL activation, triglyceride hydrolysis, FFA release
No GHR Activation
Adipose-selective activity — no IGF-1, no anabolic GH effects
vs AOD-9604
Native (Frag 176-191) vs modified (Tyr + 177-191) research design
Adipose Biology
Fat cell lipolysis mechanism in adipose tissue models
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 12629-01-5 |
| Molecular Formula | C₈₆H₁₄₄N₂₆O₂₈S |
| Peptide Type | Synthetic Peptide / Growth Hormone Fragment |
| Identity | MS molecular weight confirmed — every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
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