HGH Fragment 176-191 2mg | 20-Vial Kit | Lipolytic GH Peptide | Fat Loss Research

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HGH Fragment 176-191 2mg | 20-Vial Kit — GH C-terminal fragment (residues 176-191) — activates β3-adrenergic receptors to drive fat oxidation without activating growth hormone receptor (GHR) or stimulating IGF-1. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

🌏 International shipping: 7–14 days

$250.00

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

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What is HGH Fragment 176-191??

HGH Fragment 176-191 (CAS 66004-57-7) is the C-terminal amino acid sequence 176–191 of the 191-amino acid human growth hormone molecule. Molecular formula C₇₈H₁₂₃N₂₃O₂₃S₂, MW 1,817.12 g/mol. Unlike full HGH, this fragment retains the lipolytic (fat-burning) activity of growth hormone without binding the GH receptor or stimulating IGF-1 production — making it a research tool for studying adipocyte lipolysis mechanisms that are independent of the GH/IGF-1 axis. In rodent models it has demonstrated increased lipolysis in white adipose tissue and reduced hyperglycaemia.

Research Applications

Adipocyte Lipolysis

β-adrenergic/cAMP-independent fat mobilisation pathway, hormone-sensitive lipase activation

HGH Bioactivity Mapping

Fragment vs. full-length HGH functional dissection — lipolytic domain without GHR binding

Carbohydrate Metabolism

Glucose regulation and anti-hyperglycaemic effects independent of IGF-1 induction

Fat Depot Selectivity

Visceral vs. subcutaneous adipose tissue lipolysis differential studies

GH Axis Comparison

HGH Fragment 176-191 vs. intact HGH vs. GHRH analogs — IGF-1 independence profiling

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 66004-57-7
Sequence HGH aa 176–191 C-terminal fragment
Molecular Formula C₇₈H₁₂₃N₂₃O₂₃S₂
Molecular Weight 1817.12 g/mol
Peptide Type Synthetic GH C-terminal fragment / lipolytic peptide — IGF-1 independent
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 International shipping: 7–14 days

Frequently asked questions

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