Matrixyl (Palmitoyl Pentapeptide-4) 10mg | Matrikine / Collagen-Stimulating
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Matrixyl (Palmitoyl Pentapeptide-4) 10mg — Palmitoyl pentapeptide-4 (Pal-KTTKS) — TGF-β signalling activator studied for collagen I/III and fibronectin synthesis upregulation in fibroblast models for wound repair and anti-aging skin research. ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
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What is Matrixyl?
Matrixyl (Palmitoyl Pentapeptide-4) is a matrikine / collagen-stimulating peptide. Palmitoyl-Lys-Thr-Thr-Lys-Ser pentapeptide; mimics collagen breakdown fragments (matrikines) to upregulate collagen I, III, fibronectin, and hyaluronic acid synthesis via TGF-β pathway activation. Research use only.
Research Applications
Collagen Synthesis Research
Type I & III collagen upregulation, fibroblast activation, ECM remodelling
TGF-β Pathway Studies
TGF-β1 receptor activation, downstream SMAD signalling, gene expression
Skin Ageing Models
Wrinkle reduction, dermal thickness, elasticity studies in vitro/ex vivo
Wound Healing Research
Fibroblast proliferation, ECM scaffold restoration, tissue regeneration
Biomaterial & Cosmeceutical R&D
Penetration enhancer lipid conjugation, topical delivery optimisation
Quick Specs
| Form | Lyophilized powder |
| Purity | ≥99% by HPLC — every batch |
| CAS Number | 214047-00-4 |
| Molecular Formula | C₃₉H₇₅N₅O₁₀, MW 802.0 |
| Identity | MS molecular weight confirmed — every batch |
| Peptide Type | Matrikine / Collagen-Stimulating Peptide |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS — Qingdao, China |
| Storage | -20°C sealed | 2–8°C reconstituted (2–4 weeks) |
| Shelf Life | 24 months (unopened) |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
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