Melatonin 10mg | 10-Vial Kit | Pineal Hormone | Circadian & Antioxidant Research

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Melatonin (N-Acetyl-5-methoxytryptamine, CAS 73-31-4) 10mg — ≥99% HPLC purity, Janoshik COA. Research use only.

🌏 International shipping: 7–14 days

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

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What is Melatonin??

Melatonin (N-Acetyl-5-methoxytryptamine, CAS 73-31-4) is an endogenous indole neurohormone synthesised from tryptophan → serotonin → N-acetylserotonin → melatonin in the pineal gland, with peak release in darkness. Molecular formula C₁₃H₁₆N₂O₂, MW 232.28 g/mol. Melatonin acts on MT1 and MT2 G-protein-coupled receptors (Gi-linked, cAMP suppression) to entrain circadian rhythms. It is also a direct free radical scavenger (hydroxyl, peroxynitrite, superoxide), upregulates glutathione peroxidase and superoxide dismutase, and participates in immune modulation and mitochondrial protection at the cellular level.

Research Applications

Circadian Rhythm Research

MT1/MT2 receptor activation, SCN entrainment, phase shifting, jet-lag and shift-work models

Antioxidant Biology

Direct ROS/RNS scavenging, GPx/SOD upregulation, lipid peroxidation inhibition

Sleep Architecture

NREM/REM sleep modulation, sleep onset latency, Zeitgeber synchronisation studies

Oncostatic Research

MT1-mediated oestrogen receptor cross-talk, tumour proliferation inhibition in preclinical models

Mitochondrial Protection

Electron transport chain protection, mitochondrial membrane integrity, cytochrome c release

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number 73-31-4
Molecular Formula C₁₃H₁₆N₂O₂
Molecular Weight 232.28 g/mol
Compound Type Endogenous pineal neurohormone / MT1/MT2 receptor agonist
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | protect from light
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute this peptide?
Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.
How should this peptide be stored?
Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.
What purity is this QSC compound and how is it verified?
All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌏 International shipping: 7–14 days

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