MOTS-c 10mg | 10-Vial Kit | Metabolic Regulator

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QSC MOTS-c (Mitochondria-derived peptide) — ≥99% HPLC purity, MS confirmed, Janoshik COA. Research use only.

🌍 Domestic shipping: 🇪🇺 EU  ·  🇬🇧 UK  ·  🇺🇸 USA  ·  🇦🇺 AU  ·  🇨🇦 Canada 5–7 days
🌏 International shipping: 7–14 days

* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

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What is MOTS-c?

MOTS-c (Mitochondria-derived peptide (mitochondrial 12S rRNA-encoded)) is a 16-amino acid mitochondria-encoded peptide. Mitochondria-derived peptide encoded by the 12S rRNA gene — translocates to the nucleus under metabolic stress to regulate AMPK and folate-methionine cycle activity. Declines with age. Extends lifespan in aged male mice, improves insulin sensitivity, exercise capacity, and thermogenic response to cold stress.

Research Applications

Retrograde Signalling

Mitochondria-to-nucleus communication under metabolic stress

AMPK Activation

Energy sensor activation, cellular fuel switch, autophagy

Insulin Sensitivity

Glucose uptake, GLUT4 translocation, insulin resistance models

Exercise & Metabolism

VO2 max, muscle metabolism, endurance capacity research

Longevity Biology

Age-related decline, mitokine signalling, lifespan extension

Quick Specs

Form Lyophilized powder
Purity ≥99% by HPLC — every batch
CAS Number Not publicly standardized
Molecular Formula Sequence-specific (16-amino-acid mitochondrial-derived peptide)
Peptide Type Mitochondria-Derived Peptide / Metabolic Regulator
Identity MS molecular weight confirmed — every batch
COA Janoshik-independent, publicly verifiable
Manufacture In-house Fmoc SPPS — Qingdao, China
Storage -20°C sealed | 2–8°C reconstituted (2–4 weeks)
Shelf Life 24 months unopened

Certificate of Analysis (COA)

Frequently Asked Questions

How do I reconstitute MOTS-c?
Add 1–2mL bacteriostatic water to the lyophilized MOTS-c vial. Swirl gently until dissolved. MOTS-c is a 16-amino acid peptide that dissolves readily to a clear, colourless solution.
How should MOTS-c be stored?
Store lyophilized at −20°C. Reconstituted: 2–8°C for up to 28 days. Avoid repeated freeze-thaw cycles and protect from UV light.
What purity is QSC MOTS-c and how is it verified?
QSC MOTS-c is ≥99% HPLC pure with MS-confirmed 16-amino acid sequence on every batch. COA is published on the product page and verifiable at verify.janoshik.com.
🧪 Peptide Research Tools: Use QSC’s free peptide calculators — reconstitution, BAC water, dosing, half-life, and mixing charts.
🌍 Domestic shipping: 🇪🇺 EU  ·  🇬🇧 UK  ·  🇺🇸 USA  ·  🇦🇺 AU  ·  🇨🇦 Canada 5–7 days
🌏 International shipping: 7–14 days

Frequently asked questions

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