Vesugen 10mg | 20-Vial Kit | KED Vascular Bioregulator | Endothelial & Anti-Aging Research
🇺🇸 1-Region Domestic Shipping
Vesugen (Lys-Glu-Asp / KED tripeptide, MW 390.39 g/mol) 10mg — >=99% HPLC purity, MS confirmed, Janoshik COA. Research use only.
* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.
{“@context”: “https://schema.org”, “@type”: “FAQPage”, “mainEntity”: [{“@type”: “Question”, “name”: “How do I reconstitute this peptide?”, “acceptedAnswer”: {“@type”: “Answer”, “text”: “Add 1–2mL bacteriostatic water to the lyophilized vial by directing water down the inner wall of the vial. Swirl gently until the powder fully dissolves — do not shake or vortex. The solution should be clear and colourless. Use immediately or refrigerate at 2–8°C.”}}, {“@type”: “Question”, “name”: “How should this peptide be stored?”, “acceptedAnswer”: {“@type”: “Answer”, “text”: “Store lyophilized peptide vials at −20°C for long-term storage. Once reconstituted, store at 2–8°C (refrigerator) and use within 21–28 days. Avoid repeated freeze-thaw cycles, direct light, and heat exposure.”}}, {“@type”: “Question”, “name”: “What purity is this QSC compound and how is it verified?”, “acceptedAnswer”: {“@type”: “Answer”, “text”: “All QSC compounds are tested to ≥99% purity by HPLC peak area analysis on every production batch. Molecular identity is confirmed by mass spectrometry. A Certificate of Analysis (COA) is published on the product page and independently verifiable at verify.janoshik.com using the batch reference number.”}}]}
What is Vesugen??
Vesugen (Lys-Glu-Asp, KED, molecular formula C15H26N4O8, MW 390.39 g/mol, PubChem CID 87571363) is a synthetic tripeptide bioregulator developed by Prof. Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. Derived from vascular wall-associated proteins, Vesugen is investigated for its ability to interact with DNA minor grooves and promoter regions – modulating gene expression in endothelial cells and vascular smooth muscle. Key reported mechanisms include normalisation of endothelin-1 and connexin expression, restoration of eNOS gene activity, upregulation of SIRT1 (sirtuin-1), and reduction of Ki-67-driven senescent cell proliferation. It is classified as a Cytogen (synthetic short-peptide bioregulator) in the Khavinson bioregulator system.
Research Applications
Vascular Endothelial Gene Regulation
Endothelin-1 normalisation, connexin expression restoration, eNOS upregulation, ICAM-1/VCAM-1 adhesion molecule modulation
SIRT1 & Anti-Ageing Pathways
Sirtuin-1 upregulation, calorie-restriction-mimetic gene expression, SASP reduction in senescent endothelial cells
Atherosclerosis & Vascular Ageing
Endothelial dysfunction models, arterial stiffness, plaque formation studies – aged Wistar rat vascular experiments
Mesenchymal Stem Cell Research
MSC proliferation enhancement, senescence marker reduction, Ki-67 expression and cell differentiation control
Epigenetic & DNA Interaction
Peptide-DNA minor groove binding, histone complex interaction, promoter region modulation in vascular nuclei
Quick Specs
| Form | Lyophilized powder |
| Purity | >=99% by HPLC – every batch |
| Sequence | Lys-Glu-Asp (KED) |
| Molecular Formula | C15H26N4O8 |
| Molecular Weight | 390.39 g/mol |
| PubChem CID | 87571363 |
| Peptide Type | Synthetic tripeptide bioregulator / Khavinson Cytogen – vascular |
| Identity | MS molecular weight confirmed – every batch |
| COA | Janoshik-independent, publicly verifiable |
| Manufacture | In-house Fmoc SPPS – Qingdao, China |
| Storage | -20C sealed | 2-8C reconstituted (2-4 weeks) |
| Shelf Life | 24 months unopened |
Certificate of Analysis (COA)
Frequently Asked Questions
Frequently asked questions
A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
A seemingly elegant design can quickly begin to bloat with unexpected content or break under the weight of actual activity. Fake data can ensure a nice looking layout but it doesn’t reflect what a living, breathing application must endure. Real data does.
Websites in professional use templating systems. Commercial publishing platforms and content management systems ensure that you can show different text, different data using the same template. When it’s about controlling hundreds of articles, product pages for web shops.
Reviews
Clear filtersThere are no reviews yet.